I also have much-rescheduled trips to Vilnius, Stockholm and Bratislava booked for the upcoming spring.
Man you know what COVID-19 has killed for me? The multi-country international trip. I used to do things like spend 2 weeks visiting 6 different countries but that seems totally unsustainable in a world with every country having slightly different rules and tests and such being required even to cross Schengen borders.
For April 2022, I am thinking Panama. In another time it might be Panama and Costa Rica, or Panama and Colombia, but for right now it's logistically difficult to meet the test/vax proof requirements for even one country.