As far as chief's comment any draft pick is a lottery ticket... I get the point, but it's insane to say a 32nd pick nets the same chance for talent as a 5 pick. The higher the pick, the better talent you get. Even if we didn't get Strasburg and Harper, two or three years of a #2 or 3 pick nets drastically improved teams five years down the road than picking 16, what one might expect with a mediocre instead of horrid team. Yes, no one is guaranteed to pan out, but it's insane to say years of a second pick would result in a tea that kicks years of a 16th picks ass excluding any other players.
Strawman #1 - there was no way the 2006-2010 Nats were ever going to be good enough to get higher than the 20th pick (only 30 teams in baseball) - that would be a top-ten record and a likely playoff spot. The argument is really whether they were significantly advantaged by having two top5s (which turned out to be #1s) vs. two in the 5-10 slot.
Strawman #2 - "excluding any other players." Great jumping jiminy, that's the whole point. Why does it have to be "excluding all other players?" In what bylaw is it written that the Nats couldn't have added mid-level guys, ended up with a comfortably mediocre 72-90, drafted Mike Minor at #7 and then thrown more serious money at Fielder or Reyes or Greinke or Hamels or whoever.
Who's to say that the Atlanta Braves, who did exactly that and added Minor to their stable of young arms, traded for Jurrjens and signed Hudson and others as free agents won't be better than the Nats for years to come? Oh, by the way, the Braves never bottomed out to worse than 72-90 - that was their one down year among consistent NL East contention. They also seem to find good arms in the middle of the draft and elsewhere. Amidst their whole rotation, Minor's the only first-rounder.
You don't have to suck for years before you get good. If you do suck for years, that's not a guarantee that you will get good.