Big Meech - While Mattheus looks like an idiot after breaking his hand, he was effective last year as a rookie and a product of the Joe Beimel trade. He is one of those TJ guys when Rizzo picked him up who worked out well.
In addition to Strasburg, he also drafted Storen in 2009. That was not an automatic pick. Can't call it a bust.
The Gio trade and the Span trade also stripped out high end talent that would be in AA or AAA now.
We still have Karns in AA. I don't think you can blast the pitching draft choices. We lack some system product depth in the high minors more or less because his highest draft choices (Stras, Storen) were quick to the majors and several other high end prospects ended up part of deals.