I think it would be totally hilarious if Justin Verlander pitched a no-hitter and lost.
EDIT: Not happening
Check this one out
On July 1, 1990, Andy Hawkins pitched a no-hitter for the Yankees against the Chicago White Sox at Comiskey Park but lost the game. Hawkins dominated the White Sox into the eighth inning, but after retiring the first two batters, Sammy Sosa reached on a fielding error by Yankees third baseman Mike Blowers. After Hawkins loaded the bases by walking the next two batters, Robin Ventura lofted a fly ball to left field. Rookie Jim Leyritz, fighting a blustery wind, had the ball glance off his glove for an error, allowing all three baserunners to score. The next batter, Ivan Calderón, hit a fly ball to right field, which Jesse Barfield lost in the sun and dropped for another error, allowing Ventura to score. The Yankees could not score in the ninth, giving Hawkins the loss despite not allowing a hit.
The 4-0 loss was the largest margin of a no-hitter loss in the 20th century, and Hawkins became the first Yankees pitcher to lose a no-hitter. On September 4, 1991 the Committee for Statistical Accuracy, appointed by Commissioner Fay Vincent, changed the definition of a no-hitter to require that a pitcher throw at least nine full innings and a complete game. Since Hawkins played for the visiting team, the White Sox never batted in the ninth inning and Hawkins lost the credit for a no-hitter.