The problem is getting ahead in the count. Out of 20.216 pitches, only 3,801 (19%) have been from behind in the count. He's the kind against which you need to open up the hitting zone a bit and be more aggressive. If you try to wait him out, you're K'd.
He has one of the best scatter diagrams of pitch locations we'll ever see.
I have been noticing that as I have looked through the graphs for him. His consistency and command of the strike zone with each pitch is quite amazing. It is no wonder he is one of the better pitchers in the league. He doesn't through his slider much, but it rarely ever is in the strikezone when he does. By the time he is throwing it, though, he already has the batters guessing.