I work full-time at home in a spare bedroom that i converted into a home office. I do have to travel a fair bit so it's a trade-off. I miss going out to lunch and having co-workers to talk with, and listening to Howard Stern on the commute, but overall I don't miss being stuck in traffic for 2 hours a day.
The problem is staying in that room. There's no fun stuff just outside your office at work. Maybe putting on a suit and tie at home helps. . ..